Efficacy and safety of a 21/7-active combined oral contraceptive with continuous low-dose ethinyl estradiol von März 2016
Also quasi, so wie ich das verstanden habe, Anwender-Pearl-Index:
A total of 2858 women enrolled and 1680 completed the study. Forty-six pregnancies in 2401 women aged 18–35 years occurred after COC initiation and up to 7 days after last DSG/EE or EE-only tablet was taken. When cycles in which another contraceptive method was used were excluded, the PI was 2.68 [95% confidence interval (CI), 1.96–3.57]. The cumulative pregnancy rate after 1 year of treatment was 2.47% (95% CI, 1.85–3.29) for all users aged 18–35 years. When only cycles during which women considered compliant were included, the PI was 2.00 (95% CI, 1.39–2.80). AEs were similar to those seen with other oral contraceptives.